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Biochemistry
The graduates of the PhD study field of Biochemistry are able to work independently and creatively in a scientific way. They are proficient in the scientific methods of research in biochemistry, molecular biology, biophysical chemistry, biotechnology and clinical biochemistry, with a focus on advanced research methods in biochemistry. Graduates are able to find prospective directions for the development of the scientific field, formulate a scientific problem, set up a research project, select appropriate experimental techniques to solve a given scientific problem and lead a research team. Graduates of doctoral studies will find employment in research institutions as well as in educational institutions at home and abroad. Graduates are also able to assist in the teaching of specialised chemistry courses at universities and to carry out research independently. The acquired theoretical and practical knowledge enables him/her to manage teams of technical staff, graduates of the Master's and Bachelor's degree in chemistry and to take responsibility for complex solutions.
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successful completion of the entrance exam
Additional information
Biochemistry and molecular biology: Cell, organelle functions. Structure of proteins. Amino acids - physicochemical properties. Enzymes - nature of enzyme catalysis. Enzyme kinetics - effect of substrate concentration on initial rate. Michaelis-Menten equation. Characterisation of Km and methods of experimental determination. Regulation of enzyme activity. Allosteric regulation of enzyme activity. Nucleic acids - functions and primary structure of DNA and RNA. Mechanism of DNA replication. Mechanism of DNA transcription. Translation - mechanism, stages of the process. Methods of genetic engineering - preparation of recombinant DNA. Use of plasmids, bacteriophages, restrictases and reverse transcriptase in genetic engineering. Basic principles of metabolism. Glycolysis, gluconeogenesis, pentose phosphate pathway, citrate cycle. Oxidative phosphorylation - chemiosmotic theory of ATP synthesis. Photosynthesis. Digestion of fats and transfer of fatty acids into the cell, fatty acid activation. Carnitine cycle and beta-oxidation of fatty acids. Glyoxalate cycle. Nitrogen fixation. Amino acid metabolism. Urea cycle.
Biophysical chemistry: Basic separation methods - chromatography, electrophoresis. Spectral methods - their application in the study of biomacromolecules. Fluorescence. Calorimetry. Methods to determine the size of biomacromolecules, oligomeric state, local and global stability, dynamics.
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Apply the application for study
01.03.2025 - 31.05.2025
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Performance of the entrance exam
16.06.2025 - 27.06.2025
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We will send you all the information about important events and deadlines.
- CV
- verified copy of the degree for applicant of other universities
- photocopy of the Diploma Supplement to candidates from other universities
Annual tuition fees
Standard length of study: cost free
The fee for admission procedure
application form: 50 €
E-application form: 40 €
Billing information
Bank: Treasury. Bank code: 8180
Account number: SK 28 8180 0000 0070 0007 8491
Variable symbol: 2996
Constant symbol: 0308
Specific symbol: birth number without slash
Recipient message: name and surname of the applicant
Always up-to-date news about university Pavol Jozef Šafárik University in Košice on your email.
We will send you all the information about important events and deadlines.
0911 154 882
0910 288 664
037 / 6414881
037 / 6414890
(7.30 - 15.30 h.)
Responsibility for content: Ing. Lucia Dancáková – lucia.dancakova@upjs.sk
Last update: 11.11.2024 10:59