Farmaceutická chémia

During the PhD. study, the student acquires knowledge in the field of Pharmaceutical Chemistry in this study program. The main goal is focused on the design, synthesis, analysis, and evaluation of biologically active compounds. In the study, the students learn to form a scientific problem independently, to form a scientific hypothesis, prepare and realise a scientific experiment. These activities' main aim are theoretical and practical mastering methods for chemical studies of biologically active compounds. The students' abilities after completion of the study will result from frame topics which are: design of novel biologically active compounds, total synthesis of biological active compounds, chemical modification of natural compounds with goal to increased their biological activities, structure determination of prepared compounds, analytical evaluation of reaction mixtures as well as isolated products, drugs and biologically active compounds, study of physicochemical properties of prepared compounds, study of interactions between biologically active compounds and lipids, proteins and DNA extracted from biological sources, evaluation of biological activities of biologically active compounds at different levels (in silico, in vitro, in vivo), evaluation of the toxicological effect of drugs and biologically active compounds on model organisms in relation to their impact on the human body and the environment. To achieve necessary research results during the study, it is required that students not only acquire theoretical knowledge, but also gain skills in the field of modern synthetic methods, preparative and analytical instrumental methods, used in pharmaceutical chemistry.

Graduates from the PhD. study programme Pharmaceutical Chemistry, doctoral university study, will master scientific work principles and methodology. They will be able to perform professional and scientific activities in pharmacy, chemistry, and pharmaceutical research. The academic knowledge and practical skills they acquired during the study will allow them to work as researchers in related medical, pharmaceutical, and natural science branches, such as e. g., inorganic chemistry, organic chemistry, analytical chemistry, biochemistry, physical chemistry, nuclear chemistry, and medical chemistry. Knowledge and skills will also be used in solving multidisciplinary problems with connection to pharmaceutical technology, pharmacology, etc. The graduates can work independently in science and bring their solutions to the branches mentioned above.

The requirement for completion of the study programme is the knowledge and further development of methods of research and development of new synthetic drugs including design, synthesis, analysis, and evaluation of bioactive compounds. A successful graduate of the doctoral studies must prove that he has not only required theoretical knowledge in the field, but also practical research skills in the field of pharmaceutical chemistry and is able to work independently. At the same time, he must be able to present results of his own research to the professional community at conferences and scientific events and publish articles in scientific journals.

Graduates from the PhD. studies may find employment in the framework of higher education as university teachers or scientific research workers at universities focused on pharmacy, medicine, healthcare science, and chemistry, and in the institutes of Slovak Academy of Sciences. At present, the graduates are required mainly at workplaces in healthcare, such as the State Institute for the Drug Control, which provides supervision over the quality, effectiveness, safety of drugs and medical devices. Graduates of the study program are also employed in pharmaceutical companies that are engaged in the synthesis and analysis of drugs and medicines, control laboratories (clinical analysis, quality control of drugs and medicines), as well as in companies that perform custom synthesis of drugs and biologically active compounds.

Graduates from the study programme Pharmaceutical Chemistry at the Faculty of Pharmacy Comenius University Bratislava will master scientific work principles and methodology. They will perform professional and scientific activities in pharmaceutical chemistry, pharmacy, and pharmaceutical research. The academic knowledge and practical skills they acquired during the study will allow them to work as scientific workers in related medical, pharmaceutical, and chemical branches as, e.g., analytical chemistry, inorganic chemistry, nuclear chemistry, organic chemistry, biochemistry, physical chemistry, medical chemistry, pharmacology, toxicology, pharmacognosy, and pharmaceutical technology. The graduates will have the ability to work independently in science, provide their solutions, and contribute to developing the scientific knowledge in the stated branches. They will be qualified enough for successful employment as the team leaders in the broader spectrum of scientific and research institutions focused on pharmaceutical, medical, or chemical sciences. They will be professionally prepared to work creatively in scientific institutes of the Slovak Academy of Science at various research positions.

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